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ISO HV Replacement O-Rings

TFM offers replacement elastomeric o-rings designed for use with centering rings (not included) to seal ISO flanges in high vacuum (HV) systems. These ISO flanges, also known as Large ISO, are commonly used for HV chamber ports and are available in two styles: ISO-K, which uses clamp fasteners, and ISO-F, which uses nut and bolt fasteners.

O-Rings Features:

  • Available in Viton (fluorocarbon), Buna-N (nitrile rubber), and silicone materials.
  • Popular o-ring sizes for vacuum applications are listed below, but custom sizes and application support are available upon request. Contact us for assistance.

Ordering Table

ISO HV Replacement O-Rings

Drawing Flange OD Reference O-Ring Size O-Ring Color O-Ring Material O-Ring Cross Section O-Ring ID O-Ring OD Part Number
Tooltip ISO63 O-ring Seals, Nitrile (Buna-N) 336 Black 4900-70 Nitrile 0.210 2.850 3.270 O-B336
Tooltip ISO80 O-ring Seals, Nitrile (Buna-N) 341 Black 4900-70 Nitrile 0.210 3.475 3.895 O-B341
Tooltip ISO100 O-ring Seals, Nitrile (Buna-N) 346 Black 4900-70 Nitrile 0.210 4.100 4.520 O-B346
Tooltip ISO160 O-ring Seals, Nitrile (Buna-N) 361 Black 4900-70 Nitrile 0.210 5.975 6.395 O-B361
Tooltip ISO200 O-ring Seals, Nitrile (Buna-N) 371 Black 4900-70 Nitrile 0.210 8.475 8.895 O-B371
Tooltip ISO250 O-ring Seals, Nitrile (Buna-N) 378 Black 4900-70 Nitrile 0.210 10.475 10.895 O-B378
Tooltip ISO320 O-ring Seals, Nitrile (Buna-N) 454 Black 4900-70 Nitrile 0.275 12.475 13.025 O-B454
Tooltip ISO400 O-ring Seals, Nitrile (Buna-N) 460 Black 4900-70 Nitrile 0.275 15.475 16.025 O-B460
Tooltip ISO500 O-ring Seals, Nitrile (Buna-N) 468 Black 4900-70 Nitrile 0.275 19.455 20.005 O-B468
Tooltip ISO630 O-ring Seals, Nitrile (Buna-N) 474 Black 4900-70 Nitrile 0.275 24.940 25.490 O-B474
Tooltip ISO63 O-ring Seals, Fluorcarbon (FKM) 336 Brown 9505-75 Fluorocarbon 0.210 2.850 3.270 O-V336
Tooltip ISO80 O-ring Seals, Fluorcarbon (FKM) 341 Brown 9505-75 Fluorocarbon 0.210 3.475 3.895 O-V341
Tooltip ISO100 O-ring Seals, Fluorcarbon (FKM) 346 Brown 9505-75 Fluorocarbon 0.210 4.100 4.520 O-V346
Tooltip ISO160 O-ring Seals, Fluorcarbon (FKM) 361 Brown 9505-75 Fluorocarbon 0.210 5.975 6.395 O-V361
Tooltip ISO200 O-ring Seals, Fluorcarbon (FKM) 371 Brown 9505-75 Fluorocarbon 0.210 8.475 8.895 O-V371
Tooltip ISO250 O-ring Seals, Fluorcarbon (FKM) 378 Brown 9505-75 Fluorocarbon 0.210 10.475 10.895 O-V378
Tooltip ISO320 O-ring Seals, Fluorcarbon (FKM) 454 Brown 9505-75 Fluorocarbon 0.275 12.475 13.025 O-V454
Tooltip ISO400 O-ring Seals, Fluorcarbon (FKM) 460 Brown 9505-75 Fluorocarbon 0.275 15.475 16.025 O-V460
Tooltip ISO500 O-ring Seals, Fluorcarbon (FKM) 468 Brown 9505-75 Fluorocarbon 0.275 19.455 20.005 O-V468
Tooltip ISO630 O-ring Seals, Fluorcarbon (FKM) 474 Brown 9505-75 Fluorocarbon 0.275 24.940 25.490 O-V474
Tooltip ISO63 O-ring Seals, Silicone 336 Brick Red 1200-70 Silicone 0.210 2.850 3.270 O-S336
Tooltip ISO80 O-ring Seals, Silicone 341 Brick Red 1200-70 Silicone 0.210 3.475 3.895 O-S341
Tooltip ISO100 O-ring Seals, Silicone 346 Brick Red 1200-70 Silicone 0.210 4.100 4.520 O-S346
Tooltip ISO160 O-ring Seals, Silicone 361 Brick Red 1200-70 Silicone 0.210 5.975 6.395 O-S361
Tooltip ISO200 O-ring Seals, Silicone 371 Brick Red 1200-70 Silicone 0.210 8.475 8.895 O-S371
Tooltip ISO250 O-ring Seals, Silicone 378 Brick Red 1200-70 Silicone 0.210 10.475 10.895 O-S378
Tooltip ISO320 O-ring Seals, Silicone 454 Brick Red 1200-70 Silicone 0.275 12.475 13.025 O-S454
Tooltip ISO400 O-ring Seals, Silicone 460 Brick Red 1200-70 Silicone 0.275 15.475 16.025 O-S460
Tooltip ISO500 O-ring Seals, Silicone 468 Brick Red 1200-70 Silicone 0.275 19.455 20.005 O-S468
Tooltip ISO630 O-ring Seals, Silicone 474 Brick Red 1200-70 Silicone 0.275 24.940 25.490 O-S474
Tooltip ISO63 O-ring Seals, Kalrez 336 Black 4079 Kalrez 0.210 2.850 3.270 O-K336
Tooltip ISO63 O-ring Seals, Ethylene Propylene (EPDM) 336 Black 5600-70 EPDM 0.210 2.850 3.270 O-E336
Tooltip ISO80 O-ring Seals, Kalrez 341 Black 4079 Kalrez 0.210 3.475 3.895 O-K341
Tooltip ISO80 O-ring Seals, Ethylene Propylene (EPDM) 341 Black 5600-70 EPDM 0.210 3.475 3.895 O-E341
Tooltip ISO100 O-ring Seals, Kalrez 346 Black 4079 Kalrez 0.210 4.100 4.520 O-K346
Tooltip ISO100 O-ring Seals, Ethylene Propylene (EPDM) 346 Black 5600-70 EPDM 0.210 4.100 4.520 O-E346
Tooltip ISO160 O-ring Seals, Kalrez 361 Black 4079 Kalrez 0.210 5.975 6.395 O-K361
Tooltip ISO160 O-ring Seals, Ethylene Propylene (EPDM) 361 Black 5600-70 EPDM 0.210 5.975 6.395 O-E361
Tooltip ISO200 O-ring Seals, Kalrez 371 Black 4079 Kalrez 0.210 8.475 8.895 O-K371
Tooltip ISO200 O-ring Seals, Ethylene Propylene (EPDM) 371 Black 5600-70 EPDM 0.210 8.475 8.895 O-E371
Tooltip ISO250 O-ring Seals, Kalrez 378 Black 4079 Kalrez 0.210 10.475 10.895 O-K378
Tooltip ISO250 O-ring Seals, Ethylene Propylene (EPDM) 378 Black 5600-70 EPDM 0.210 10.475 10.895 O-E378
Tooltip ISO320 O-ring Seals, Kalrez 454 Black 4079 Kalrez 0.275 12.475 13.025 O-K454
Tooltip ISO320 O-ring Seals, Ethylene Propylene (EPDM) 454 Black 5600-70 EPDM 0.275 12.475 13.025 O-E454
Tooltip ISO400 O-ring Seals, Kalrez 460 Black 4079 Kalrez 0.275 15.475 16.025 O-K460
Tooltip ISO400 O-ring Seals, Ethylene Propylene (EPDM) 460 Black 5600-70 EPDM 0.275 15.475 16.025 O-E460
Tooltip ISO500 O-ring Seals, Kalrez 468 Black 4079 Kalrez 0.275 19.455 20.005 O-K468
Tooltip ISO500 O-ring Seals, Ethylene Propylene (EPDM) 468 Black 5600-70 EPDM 0.275 19.455 20.005 O-E468
Tooltip — O-ring Seals, Kalrez 474 Black 4079 Kalrez 0.275 24.940 25.490 O-K474
Tooltip — O-ring Seals, Ethylene Propylene (EPDM) 474 Black 5600-70 EPDM 0.275 24.940 25.490 O-E474

 

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FAQ

Tube fittings are designed for tubes (measured by outside diameter and wall thickness) used in high-pressure and instrumentation applications, whereas pipe fittings are for pipes (identified by nominal pipe size) primarily used in fluid transport.

 

Common valve types include ball valves, gate valves, check valves, butterfly valves, and globe valves. Each serves a specific function—from quick shutoff (ball/gate valves) to flow regulation (globe valves).

 

  • For tubing, measure the outside diameter; for pipes, refer to the nominal pipe size (using conversion charts if needed). Always match the valve or fitting size to your pipe’s dimensions and flow requirements.

  • Frequently used thread types include NPT (National Pipe Tapered), BSP (British Standard Pipe), and UNC, along with slip-fit options that rely on compression or fusion rather than threads.

Interchangeability depends on manufacturer specifications and certification. Always verify compatibility via manufacturer guides or certified interchangeability charts.

 

  • A coupling is a short, straight fitting used to join two pipes or tubes. It provides a secure, leak-tight connection and can sometimes serve to extend or repair piping runs.

Consider valve type, pressure and temperature ratings, material compatibility with your fluid, actuation method (manual or automatic), and maintenance requirements.

 

  • Valves regulate flow by opening, closing, or partially obstructing the pathway. Their mechanisms (such as the rotation of a ball or the linear movement of a gate) determine the speed and precision of flow control.

  • A flange is a flat, circular component used to connect pipes, valves, or other equipment. Bolted together with gaskets, flanges provide a secure, leak-proof joint that facilitates both assembly and maintenance.

  • Manual valves require physical operation via handles or levers, whereas actuated valves use mechanisms—pneumatic, electric, or hydraulic—to open and close automatically or remotely.

  • Issues include leaks caused by improper installation, over-tightening, degraded seals, material incompatibility, and fatigue from repeated cycling. Regular inspection and proper installation practices help mitigate these problems.

Regular maintenance involves periodic inspections, cleaning or replacing worn seals, ensuring proper torque during installation, and adhering to manufacturer guidelines and local plumbing codes to preserve system integrity.

 

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